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Active Ingredients in Salvia Sclarea oil

Salvia Sclarea oil presents a natural vegetable oil formula of unique and rare active ingredients. The presence of those ingredients suggest that the oil may provide an Anti-bacterial, Anti-oxidant Antiseptic, Antiviral, Anti-mutagenic Anti - inflammation,                                                                                                                                                                                               Antifungal and Astringent qualities.

One of those ingredients is Sclareol; Sclareol is a rare substance which used to be produced from whales. Sclareol has many unique medical properties and its presence in the Salvia Sclarea oil differentiate the oil from any known vegetable oil today.


Substance

Alpha Linolenic Acid (ALA) Omega 3


Oleic Acid Omega 9








Linalool and Linalyl acetate





Omega 3 to Omega 6 Ratio


Tannic Acid




Sclareol
















Lectin extracted from the seeds of Salvia sclarea

 



Manoo
l







Caryophyllene oxide





Sterols







Sterols present in Salvia Sclarea seed oil









Tocopherols (Vitamin E)




Coenzyme Q10

Benefits

Omega-3 fatty acids are PUFA, required for the structure and function of the body's cells and are important in maintaining our health. Salvia Sclarea Oil contain 50% Omega 3 ALA

•• Oleic acid may hinder the progression of ALD, or Adrenoleukodystrophy, a fatal disease that affects the Brain and
adrenal glands.
•• Oleic acid may help boost memory.
•• Oleic acid may be responsible for the hypotensive (Blood pressure reducing) effects of olive oil.
•• Salvia Sclarea Oil contain 25% Omega 9

Found to be effective as Anti - inflammation, Antibacterial, Antifungal.Behave as synergistic and strengthening other bioactive materials. (Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils Dipartimento di Scienze del Farmaco, Università degli Studi di Sassari, Sassari, Italy)


Salvia Sclarea seed oil has an excellent 3:1 Omega 3 to Omega 6 ratio

Tannic acid has Anti-bacterial, Anti-oxidant Antiseptic, Antiviral, Antimutagenic and Astringent properties (The effects of resveratrol and tannic acid on apoptosis in colon adenocarcinoma cell line.Department of Medical Biology, Eskisehir Osmangazi University, Medical Faculty, Eskisehir, Turkey)

•• Sclareol has Antioxidant, Antibacterial and Antifungal properties.
•• Sclareol posses cyto-toxic and cyto-static activity: Induced Apoptosis in human leukemic cells.
•• Sclareol enhanced the activity of known Anticancer Drugs, doxorubicin, etoposide and cisplatinum, against MDD2 breast cancer cell line.

Sclareol demonstrated a good Antibacterial activity against:
•• Staphylococcus aureus ATCC 25923,
•• Pseudomonas aeruginosa ATCC 27950,
•• Escherichia coli ATCC 25922
•• Enterococcus faecalis ATCC 29212.
•• Sclareol demonstrated significant cytotoxic activity against Hep-2 cells.(J Pharm Sci. 2007 Apr;20(2):146-8. Links)
•• Antibacterial and cytotoxic activity of the acetone extract of the flowers of Salvia sclarea and some natural products

The lectin extracted from the seeds of Salvia sclarea (SSL) recognizes the Tn antigen (GalNAc alpha1-->Ser/Thr) expressed in certain human carcinomas. (J Biomed Sci. 2005;12(1):167-84. LinksLectinochemical studies on the glyco-recognition factors of a Tn (GalNAcalpha1-->Ser/Thr) specific lectin isolated from the seeds of Salvia sclarea).

Manool has proven as a platelet aggregation inhibitor and effective Antimicrobial with: Staphylococcus Aureus, Candida Albicans and Proteus mirabilis (Synthesis of manool-related labdane diterpenes as platelet aggregation inhibitors Shionogi
Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan), (Transformations of manool. tri- and tetracyclic norditerpenoids with in vitro activity against Plasmodium falciparum Department of Chemistry, Rhodes University,
Grahamstown, South Africa).

Caryophyllene oxide, an oxygenated terpenoid, well known as preservative in food, drugs and cosmetics, Found to be effective as an Antifungal against dermatophytes (Use of caryophyllene oxide as an antifungal agent in an in vitro experimental model of onychomycosis. Authors: Yang, Depo1; Michel, Laura1; Chaumont, Jean-Pierre2; Millet-Clerc, Joëlle1)

Plant sterols reduce the uptake of cholesterol into the body. The cholesterol that is not absorbed or taken up is removed from the body. As a result blood total and bad (LDL) cholesterol decrease, while good (HDL) cholesterol is not affected. (Extensive research shows that functional foods fortified with plant sterols and plant sterol supplements, can effectively
reduce cholesterol up to 15% (Katan MB et al. 2003, Mayo Clin Proc. 2003 Aug;78(8):965-78. Review)

•• Campestanol
•• Stigmasterol D-7-Campesterol
•• D-5, 23-Stigmastadienol
•• Chlerosterol
•• B-Sitosterol
•• Sitostanol
•• D-5-Avenasterol
•• D-5,24-Stigmastadienol
•• D-7-Stigmastenol
•• D-7-Avenasterol

Tocopherols occur in Salvia Sclarea are Alpha, Beta, Gamma and Delta forms, determined by the number of methyl groups on the chromanol ring all of them Coenzyme Q10, also referred to as Co Q10 is a vitamin-like compound which is present in all cells.

Q10 has several different actions in the body. Its most notable effects are:
•• Antioxidant - it scavenges free radicals
•• Improves the efficiency of cellular energy production in the
•• mitochondria of the cell
•• Regulates genes concerned with energy production
•• Stabilizes membranes